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Modulare Mikrofluidik-Plattform im Laboratory Disc-Format für die biosensorische Bestimmung von Propionsäure-Konzentrationen
Other Titles
Modular microfluidic platform in the laboratory disc format for the biosensory determination of propionic acid concentrations
Publikationstyp
Conference Paper
Date Issued
2015-10
Sprache
German
Author(s)
Start Page
793
End Page
795
Citation
MikroSystemTechnik Kongress 2015 "MEMS, Mikroelektronik, Systeme", Proceedings: 793-795 (2015)
Contribution to Conference
Scopus ID
Publisher
VDE-Verl.
Microfluidics and lab-on-a-chip technologies are key technologies for the automated processing of small sample volumes. They can be used for chip-based test and analysis methods and can be integrated in transportable equipment systems for on-site and point-of-care applications. The propionic acid is a key analyte for the efficient operation of a biogas plant, because the propionic acid concentration increases when the fermenter is not operated under optimal conditions and is likely to acidify. The operating principle of the sensor is based on the translation of the propionic acid concentration into a current signal by an exoelectrogenic bacterial strain and the subsequent quantification of the signal. The presented modular platform of a fluidic sensor, designed as a sandwich glass chip, consists of a flow chamber for the transport of the analyte and an above mounted electrode structure for electrical detection of the signal of the bacterial strain. The development of lab-on-a-chip systems in the format of Microfluidic Laboratory Discs and appropriate technologies for the production of electrode arrays on polycarbonate-substrates allows for the production of low-cost disposables in large quantities. Based on the single sensor we show the conceptual implementation of the measuring principle in a microfluidic disc as a disposable for on-site lab-on-a-chip analysis.
DDC Class
570: Biowissenschaften, Biologie
600: Technik