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Multivalent glycan arrays
Publikationstyp
Journal Article
Date Issued
2019-01-01
Sprache
English
Journal
Volume
219
Start Page
9
End Page
32
Citation
Faraday Discussions 219: 9-32 (2019)
Publisher DOI
Scopus ID
ISSN
13596640
Glycan microarrays have become a powerful technology to study biological processes, such as cell-cell interaction, inflammation, and infections. Yet, several challenges, especially in multivalent display, remain. In this introductory lecture we discuss the state-of-the-art glycan microarray technology, with emphasis on novel approaches to access collections of pure glycans and their immobilization on surfaces. Future directions to mimic the natural glycan presentation on an array format, as well as in situ generation of combinatorial glycan collections, are discussed.
DDC Class
600: Technology