Agar aerogel powder particles for future life science applications : fabrication and investigations on swelling behavior and cell compatibility

The use of bio-based raw materials in the manufacture of customized aerogels has increased significantly over the last decade. Combining the advantages of biopolymer sustainability and lower costs when producing aerogels in particulate form, agar aerogel particles were fabricated in this study. They were prepared by successive thermal gelation, ethanol solvent exchange, wet milling and supercritical CO2 assisted drying. The particles still maintain high porosity (~ 1.0 cm3 g−1) and high specific surface areas (210–270 m2 g−1). The stability in wound fluid substitutes, liquid holding capacity, and cytocompatibility of these agar-based aerogel particles may make them an advantageous wound-dressing matrix that can be further customized for particular applications by adding wound-active/reactive substances, such as antibiotics, antioxidants, immunoreactive drugs or growth factors. Graphical abstract: (Figure presented.)

Subjects

Aerogel

Agar

Biopolymer

Supercritical CO 2

Wound dressing

DDC Class

660: Chemistry; Chemical Engineering

610: Medicine, Health

Funding(s)

Projekt DEAL

Publication version

publishedVersion

Lizenz

https://creativecommons.org/licenses/by/4.0/

Name

s00289-024-05188-y.pdf

Type

Main Article

Size

1.45 MB

Format

Adobe PDF

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Agar aerogel powder particles for future life science applications : fabrication and investigations on swelling behavior and cell compatibility