Biodegradation of polyhydroxyalkanoates: current state and future prospects

Polyhydroxyalkanoates (PHAs) are biobased and biodegradable polymers that offer a sustainable alternative to conventional plastics, addressing the escalating concerns over plastic pollution. While their environmental advantages are well-documented, the efficient degradation of PHAs in natural and engineered environments remains a critical component of their lifecycle. This review provides a comprehensive overview of PHA-degrading bacteria isolated from diverse ecosystems and highlights the pivotal role of PHA depolymerases in achieving PHA circularity. Microbial adaptation to diverse environmental conditions, such as extreme temperatures, salinity, and pH, significantly influences enzymes properties, including the stability, activity, and substrate specificity of PHA-degrading enzymes. These adaptations often enhance enzyme, performance, enabling functionality under challenging conditions. Consequently, extremophilic microorganisms are invaluable resources for discovering and engineering robust PHA depolymerases for industrial and environmental applications. This review underscores the urgent need for further research to improve the ecological and economic sustainability of PHA waste management.

Subjects

biodegradation | circular bioeconomy | extremophiles | PHA depolymerases | polyhydroxyalkanoates (PHAs)

DDC Class

620.1: Engineering Mechanics and Materials Science

660: Chemistry; Chemical Engineering

579: Microorganisms, Fungi and Algae

Publication version

publishedVersion

Lizenz

https://creativecommons.org/licenses/by/4.0/

Name

fmicb-2-1542468.pdf

Size

3.41 MB

Format

Adobe PDF

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Biodegradation of polyhydroxyalkanoates: current state and future prospects