Publisher DOI: 10.1098/rspa.2015.0641
Title: Verification of cardiac mechanics software: Benchmark problems and solutions for testing active and passivematerial behaviour
Language: English
Authors: Land, Sander 
Gurev, Viatcheslav 
Arens, Sander 
Augustin, Christoph M. 
Baron, Lukas 
Blake, Robert 
Bradley, Chris 
Castro, Sebastian 
Crozier, Andrew 
Favino, Marco 
Fastl, Thomas E. 
Fritz, Thomas 
Gao, Hao 
Gizzi, Alessio 
Griffith, Boyce E. 
Hurtado, Daniel E. 
Krause, Rolf 
Luo, Xiaoyu 
Nash, Martyn P. 
Pezzuto, Simone 
Plank, Gernot 
Rossi, Simone 
Ruprecht, Daniel  
Seemann, Gunnar 
Smith, Nicolas P. 
Sundnes, Joakim 
Jeremy Rice, J. 
Trayanova, Natalia 
Wang, Dafang 
Wang, Zhinuo Jenny 
Niederer, Steven A. 
Keywords: Benchmark;Cardiac Mechanics;Verification;VVUQ
Issue Date: 8-Dec-2015
Source: Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences 471 (2184): 20150641 (2015-12-08)
Journal: Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences 
Abstract (english): 
Models of cardiac mechanics are increasingly used to investigate cardiac physiology. These models are characterized by a high level of complexity, including the particular anisotropic material properties of biological tissue and the actively contracting material. A large number of independent simulation codes have been developed, but a consistent way of verifying the accuracy and replicability of simulations is lacking. To aid in the verification of current and future cardiac mechanics solvers, this study provides three benchmark problems for cardiac mechanics. These benchmark problems test the ability to accurately simulate pressure-Type forces that depend on the deformed objects geometry, anisotropic and spatially varying material properties similar to those seen in the left ventricle and active contractile forces. The benchmark was solved by 11 different groups to generate consensus solutions, with typical differences in higher-resolution solutions at approximately 0.5%, and consistent results between linear, quadratic and cubic finite elements as well as different approaches to simulating incompressible materials. Online tools and solutions are made available to allow these tests to be effectively used in verification of future cardiac mechanics software.
URI: http://hdl.handle.net/11420/10525
ISSN: 1364-5021
Document Type: Article
Peer Reviewed: Yes
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