Publisher DOI: 10.1016/j.coesh.2021.100313
Title: Succinic acid fermentation from agricultural wastes: The producing microorganisms and their engineering strategies
Language: English
Authors: Wang, Jingjing 
Zeng, An-Ping  
Yuan, Wenqiao 
Keywords: Actinobacillus succinogenes;Agricultural waste;Basfia succiniciprodecens;Escherichia coli;Fermentation;Mannheimia succiniciproducens;Succinic acid
Issue Date: Feb-2022
Source: Current Opinion in Environmental Science and Health 25 : 100313 (2022-02)
Journal: Current opinion in environmental science & health 
Abstract (english): 
Microbial production of succinic acid from renewable feedstock is of great importance for sustainable development owing to its great economic and technical potential. However, to be competitive with the chemical production route, efforts are still needed to enhance the production performance, especially by strain development targeting high succinic acid concentration, yield, and productivity, as well as broad carbon source utilization. In this mini-review, the performance of four promising succinic acid-producing microorganisms, including Actinobacillus succinogenes, Basfia succiniciproducens, Escherichia coli, and Mannheimia succiniciproducens, was summarized and compared. Their strengths and weakness were discussed. In addition, strategies for microbial strain improvement including metabolic engineering and membrane engineering were introduced. Future research needs were recommended.
ISSN: 2468-5844
Institute: Bioprozess- und Biosystemtechnik V-1 
Document Type: Article
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