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  4. Robotic tissue sampling for safe post-mortem biopsy in infectious corpses
 
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Robotic tissue sampling for safe post-mortem biopsy in infectious corpses

Citation Link: https://doi.org/10.15480/882.4236
Publikationstyp
Journal Article
Date Issued
2022-01-26
Sprache
English
Author(s)
Neidhardt, Maximilian  
Gerlach, Stefan  orcid-logo
Mieling, Till Robin  
Laves, Max-Heinrich  
Weiß, Thorben  
Gromniak, Martin  
Fitzek, Antonia  
Möbius, Dustin  
Kniep, Inga  
Ron, Alexandra  
Schädler, Julia  
Heinemann, Axel  
Püschel, Klaus  
Ondruschka, Benjamin  
Schlaefer, Alexander  
Institut
Medizintechnische und Intelligente Systeme E-1  
TORE-DOI
10.15480/882.4236
TORE-URI
http://hdl.handle.net/11420/11977
Journal
IEEE transactions on medical robotics and bionics  
Volume
4
Issue
1
Start Page
94
End Page
105
Citation
IEEE Transactions on Medical Robotics and Bionics 4 (1): 94-105 (2022-01-28)
Publisher DOI
10.1109/TMRB.2022.3146440
Scopus ID
2-s2.0-85124083134
ArXiv ID
2201.12168v1
Publisher
IEEE
In pathology and legal medicine, the histopathological and microbiological analysis of tissue samples from infected deceased is a valuable information for developing treatment strategies during a pandemic such as COVID-19. However, a conventional autopsy carries the risk of disease transmission and may be rejected by relatives. We propose minimally invasive biopsy with robot assistance under CT guidance to minimize the risk of disease transmission during tissue sampling and to improve accuracy. A flexible robotic system for biopsy sampling is presented, which is applied to human corpses placed inside protective body bags. An automatic planning and decision system estimates optimal insertion point. Heat maps projected onto the segmented skin visualize the distance and angle of insertions and estimate the minimum cost of a puncture while avoiding bone collisions. Further, we test multiple insertion paths concerning feasibility and collisions. A custom end effector is designed for inserting needles and extracting tissue samples under robotic guidance. Our robotic post-mortem biopsy (RPMB) system is evaluated in a study during the COVID-19 pandemic on 20 corpses and 10 tissue targets, 5 of them being infected with SARS-CoV-2. The mean planning time including robot path planning is (5.72+-1.67) s. Mean needle placement accuracy is (7.19+-4.22) mm.
Subjects
Collaborative robot
COVID-19
forensic medicine
medical robotics
path planning
Computer Science - Robotics
Computer Science - Robotics
eess.IV
Quantitative Biology - Tissues and Organs
DDC Class
600: Technik
610: Medizin
More Funding Information
Publishing fees supported by Open Access Publishing of Hamburg University of Technology.
Publication version
publishedVersion
Lizenz
https://creativecommons.org/licenses/by/4.0/
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