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  4. Product-property guided scale-up of a fluidized bed spray granulation process using the CFD-DEM method
 
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Product-property guided scale-up of a fluidized bed spray granulation process using the CFD-DEM method

Citation Link: https://doi.org/10.15480/882.4462
Publikationstyp
Journal Article
Date Issued
2022-06-30
Sprache
English
Author(s)
Kieckhefen, Paul  orcid-logo
Pietsch-Braune, Swantje  orcid-logo
Heinrich, Stefan  
Institut
Feststoffverfahrenstechnik und Partikeltechnologie V-3  
TORE-DOI
10.15480/882.4462
TORE-URI
http://hdl.handle.net/11420/13102
Journal
Processes  
Volume
10
Issue
7
Article Number
1291
Citation
Processes 10 (7): 1291 (2022)
Publisher DOI
10.3390/pr10071291
Scopus ID
2-s2.0-85133535827
Publisher
Multidisciplinary Digital Publishing Institute
In this work, a method to predict the surface structures of particles produced by fluidized bed spray layering granulation using the CFD-DEM method was developed. A simple state-variable/event tracking approach was implemented to capture indirect quantifiers of the progression of structure-forming microprocesses. The state of the droplet at the time of impact on the particle surface, as well as the time required for drying, is correlated to product properties that quantify surface structure morphology such as roughness. A workflow for scale-up of fluidized bed granulation guided by product-property predictors is presented. The approach was tested on a demonstration case from the literature, where a particle core is coated with sodium benzoate solution. The experiment was scaled-up by a factor of eight to pilot-scale using the developed method. Varying the number of nozzles in use in the pilot-scale granulation affected the particle surface roughness due to the differing drying conditions encountered. On this basis, the ability of the tracked-quantity approach to capture the relationship between product properties and geometric feature or process conditions is demonstrated.
Subjects
fluidized bed spray granulation
CFD-DEMsimulation
product-property guided scale-up
particle roughness characterization
tracked quantity
DDC Class
530: Physik
600: Technik
620: Ingenieurwissenschaften
Publication version
publishedVersion
Lizenz
https://creativecommons.org/licenses/by/4.0/
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