CHO and HepG2 Single-Cell Characterization With Planar Microchip Sensors up to 40 GHz

Publikationstyp
Journal Article
Date Issued
2023-09-01
Sprache
English
Author(s)
Savić, Aleksandar 
Freiberger, Fabian  
Pörtner, Ralf  orcid-logo
Jacob, Arne  
Institut
Hochfrequenztechnik E-3  
Bioprozess- und Biosystemtechnik V-1  
TORE-URI
http://hdl.handle.net/11420/15161
Journal
IEEE journal of electromagnetics, RF and microwaves in medicine and biology  
Volume
7
Issue
3
Start Page
236
End Page
244
Citation
IEEE Journal of Electromagnetics, RF and Microwaves in Medicine and Biology 7 (3): 236-244 (2023-09-01)
Publisher DOI
10.1109/JERM.2023.3257480
Scopus ID
2-s2.0-85151530161
The article deals with broadband microwave measurements performed on single dead and living biological cells from CHO and HepG2 cell lines. It reports results obtained with coplanar waveguide reflection and transmission type sensors, respectively. A straight-forward single liquid calibration procedure allows to extract the complex cell permittivity and compare it to that of the surrounding medium. The contrast is analyzed through -value tests and in terms of the usual Cole-Cole parameters. The results demonstrate the distinguishability of the cell lines based on the permittivity.
Subjects
Biomedical measurement
broadband measurements
Complex permittivity
Electrodes
Microwave circuits
microwave sensors
Permittivity
Permittivity measurement
Sensors
single biological cell characterization
single fluid calibration
Standards
DDC Class
600: Technology