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  4. Model-based calibration and image reconstruction with immobilized nanoparticles
 
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Model-based calibration and image reconstruction with immobilized nanoparticles

Citation Link: https://doi.org/10.15480/882.5081
Publikationstyp
Journal Article
Date Issued
2023-03-19
Sprache
English
Author(s)
Albers, Hannes  
Thieben, Florian  orcid-logo
Boberg, Marija  orcid-logo
Scheffler, Konrad  
Knopp, Tobias  
Kluth, Tobias  
Institut
Biomedizinische Bildgebung E-5  
TORE-DOI
10.15480/882.5081
TORE-URI
http://hdl.handle.net/11420/15198
Journal
International journal on magnetic particle imaging  
Volume
9
Issue
1
Article Number
2303002
Citation
International Journal on Magnetic Particle Imaging 9 (1): 2303002 (2023)
Publisher DOI
10.18416/IJMPI.2023.2303002
Scopus ID
2-s2.0-85151561022
Publisher
Infinite Science Publishing
The model-based reconstruction problem is still one of the key challenges in magnetic particle imaging (MPI) when using multi-dimensional Lissajous-type excitations. One aspect, which is often highlighted in the literature, is the magnetization behavior of the magnetic nanoparticles in fluids. Another aspect, which is at least as important as the particle model itself but sometimes treated less prominently, is a very careful calibration of the model input, respectively the scanner parameters such as analog filter and applied magnetic fields. The careful consideration of both aspects is the essential requirement for a proper solution to the model-based problem. In the present work we combine previously calibrated scanner components with mono-and polydisperse particle models for immobilized nanoparticles to derive a model-based system function and an calibration routine exploiting applied magnetic field generalizability. It is experimentally validated on the Bruker preclinical MPI system using 2D Lissajous trajectories.
DDC Class
620: Ingenieurwissenschaften
Funding Organisations
Deutsche Forschungsgemeinschaft (DFG)  
Publication version
publishedVersion
Lizenz
https://creativecommons.org/licenses/by/4.0/
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