Development of optimized magnetic particle imaging tracers utilizing genetically engineered magnetosomes

Enthalten in
International journal on magnetic particle imaging 
Volume
9
Issue
1, suppl. 1
Article Number
2303066
Citation
International Journal on Magnetic Particle Imaging 9 (1, suppl. 1): 2303066 (2023)
Publisher DOI
10.18416/IJMPI.2023.2303066
Scopus ID
2-s2.0-85151498319
Publisher
Infinite Science Publishing
The imaging quality of Magnetic Particle Imaging (MPI) is not just limited by the MPI system but also by the quality of available tracers. The tracer quality can be improved by optimizing the shape, core size and shell of the nanoparticles. However, such a defined synthesis is quite challenging. Biogenic magnetic nanoparticles, so-called magnetosomes, synthesized by magnetotoactic bacteria, might provide a promising alternative. In this study, magnetosomes isolated from different Magnetospirillum gryphiswaldense mutant strains biomineralizing particles with varying core diameters were investigated with regard to their usability as tracers for MPI.
DDC Class
530: Physik
600: Technik
620: Ingenieurwissenschaften