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  4. Safe and rapid 3D imaging : upgrade of a human-sized brain MPI system
 
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Safe and rapid 3D imaging : upgrade of a human-sized brain MPI system

Citation Link: https://doi.org/10.15480/882.5085
Publikationstyp
Journal Article
Date Issued
2023-03-19
Sprache
English
Author(s)
Thieben, Florian  orcid-logo
Mohn, Fabian  orcid-logo
Förger, Fynn  orcid-logo
Hackelberg, Niklas  
Scheel, Jan-Philipp  
Gräser, Matthias 
Knopp, Tobias  
Institut
Biomedizinische Bildgebung E-5  
TORE-DOI
10.15480/882.5085
TORE-URI
http://hdl.handle.net/11420/15210
Journal
International journal on magnetic particle imaging  
Volume
9
Issue
1
Article Number
2303045
Citation
International Journal on Magnetic Particle Imaging 9 (1): 2303045 (2023)
Publisher DOI
10.18416/IJMPI.2023.2303045
Scopus ID
2-s2.0-85151472046
Publisher
Infinite Science Publishing
Magnetic Particle Imaging hardware has reached human scale and thus patient safety questions and clinical application scenarios are in the focus of current research. In this work, we present a safe real-time 3D MPI system for cerebral applications. High voltages are avoided to ensure patient safety by a low voltage-high current transmit coil design. The developed 2D drive-field generator generates a field-free-point trajectory in the sagittal xz-plane that is shifted with low frequency by a dynamic selection-field sequence along the y-axis. The scanner generates 3D images with 4 frames/second and allows for direct visualization of the clinically preferred transversal yz-plane, which is crucial for future brain examinations. Advanced reconstruction techniques reach a system sensitivity of 4 µgFe with respect to the iron mass in a sensitivity study.
DDC Class
600: Technik
620: Ingenieurwissenschaften
Funding Organisations
Deutsche Forschungsgemeinschaft (DFG)  
Publication version
publishedVersion
Lizenz
https://creativecommons.org/licenses/by/4.0/
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