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Publisher DOI: 10.1177/0954411913501293
Title: Strain changes on the cortical shell of vertebral bodies due to spine ageing: a parametric study using a finite element model evaluated by strain measurements
Language: English
Authors: Lu, Yongtao 
Rosenau, Eike 
Paetzold, Helge 
Klein, Anke 
Püschel, Klaus 
Morlock, Michael 
Huber, Gerd 
Keywords: Finite element modelling;cortical shell;lumbar spine;principal strain;spinal ageing;Adult;Aging;Compressive Strength;Computer Simulation;Elastic Modulus;Finite Element Analysis;Humans;Lumbar Vertebrae;Male;Stress, Mechanical;Tensile Strength;Models, Biological
Issue Date: 2013
Source: Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine 12 (227): 1265-1274 (2013-12)
Journal or Series Name: Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine 
Abstract (english): The probability of fractures of the cortical shell of vertebral bodies increases as ageing progresses. Ageing involves all the spinal component changes. However, the effect of the spinal component ageing on the fracture risk of the cortical shell remains poorly understood. In this study, the influence of the ageing of the spinal components on cortical shell strain was investigated. A lumbar spinal specimen (L3-L5) was mechanically tested under a quasi-static axial compressive load. Clinical computed tomography images of the same specimen were used to create a corresponding finite element model. The material properties were determined by calibrating the finite element model using the L4 cortical shell strains of the anterior centre measurement site. The remaining experiment data (axial displacement, the intra-discal pressures, L4 cortical shell strain on the lateral measurement site) were used to evaluate the model. The individual ageing process of the six spinal components (cortical shell, cancellous bone, bony endplate, posterior elements, nucleus pulposus and annulus matrix) was simulated by changing their Young's moduli and Poisson's ratios, and the effect on cortical shell strain was investigated. Results show that the cortical shell strain is more sensitive to the ageing of the cortical shell and the cancellous bone than to the ageing of the nucleus pulposus, the annulus matrix, and the bony endplates and of the posterior elements. The results can help the clinicians focus on the aspects that mainly influence the vertebral cortex fracture risk factor.
DOI: 10.15480/882.1595
ISSN: 0954-4119
Institute: Biomechanik M-3 
Type: (wissenschaftlicher) Artikel
Permission Note: Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG geförderten) Allianz- bzw. Nationallizenz frei zugänglich. This publication is with permission of the rights owner freely accessible due to an Alliance licence and a national licence (funded by the DFG, German Research Foundation) respectively.
License: In Copyright In Copyright
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