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Publisher DOI: 10.1021/acsami.6b00778
Title: A tunable scaffold of microtubular graphite for 3D cell growth
Language: English
Authors: Lamprecht, Constanze 
Taale, Mohammadreza 
Paulowicz, Ingo 
Westerhaus, Hannes 
Grabosch, Carsten 
Schuchardt, Arnim 
Mecklenburg, Matthias 
Böttner, Martina 
Lucius, Ralph 
Schulte, Karl 
Adelung, Rainer 
Selhuber-Unkel, Christine 
Keywords: aerographite;tissue engineering;3D scaffold;cyclic RGD;fibroblasts
Issue Date: 3-Jun-2016
Publisher: Soc.
Source: ACS Applied Materials and Interfaces 24 (8): 14980-14985 (2016-06-22)
Journal or Series Name: ACS applied materials & interfaces 
Abstract (english): Aerographite (AG) is a novel carbon-based material that exists as a self-supportive 3D network of interconnected hollow microtubules. It can be synthesized in a variety of architectures tailored by the growth conditions. This flexibility in creating structures presents interesting bioengineering possibilities such as the generation of an artificial extracellular matrix. Here we have explored the feasibility and potential of AG as a scaffold for 3D cell growth employing cyclic RGD (cRGD) peptides coupled to poly(ethylene glycol) (PEG) conjugated phospholipids for surface functionalization to promote specific adhesion of fibroblast cells. Successful growth and invasion of the bulk material was followed over a period of 4 days.
DOI: 10.15480/882.1989
ISSN: 1944-8252
Institute: Kunststoffe und Verbundwerkstoffe M-11 
Type: (wissenschaftlicher) Artikel
License: CC BY 4.0 (Attribution) CC BY 4.0 (Attribution)
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