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Long-Chain Alcohol-Modified Micellar Systems and Their Application in a Continuous Extraction Process
Publikationstyp
Journal Article
Date Issued
2019-02-20
Sprache
English
Author(s)
Institut
TORE-URI
Volume
58
Issue
7
Start Page
2575
End Page
2582
Citation
Industrial and Engineering Chemistry Research 7 (58): 2575-2582 (2019-02-20)
Publisher DOI
Scopus ID
The integration of an in situ extraction into biocatalytic processes is often limited by the toxicity of organic solvents. Therefore, it is desirable to use water-based extraction systems (for example, aqueous micellar two-phase systems). They can be used, for instance, for the extraction of valuable products from microalgae cultures. Recently, the nonionic surfactant ROKAnolNL5 was identified as a suitable surfactant for this purpose, since it forms an upper micellar phase, enabling an easy separation of whole-cell biocatalysts. However, its application at temperatures below 45 °C is limited by unstable phase boundaries, whereas the maximal temperature to ensure the vitality of the most microalgae cultures is 40 °C. To overcome this problem, the addition of long-chain alcohols to the surfactant-water mixture during extraction is suggested in this work. Using 1-hexanol, a continuous extraction process with the model solute trans-cinnamic acid at 40 °C in a stirred column could be realized. The results of a new suggested water/ROKAnolNL5/1-hexanol system at 40 °C (extraction yield, Y cont = 97.67% ± 0.14%; enrichment factor, log 10 T CA = 2.42 ± 0.03; number of theoretical stages, N theo = 4.45 ± 0.16) are comparable to those of the water/ROKAnolNL5 system at 45 °C (Y cont = 99.26% ± 0.24%, log 10 T CA = 2.60 ± 0.10, N theo = 5.88 ± 0.67), ensuring, however, no damage of microalgae.
DDC Class
600: Technology
More Funding Information
Funding The authors appreciate the financial support of DFG (Project No. SM 82/14-1). Notes The authors declare no competing financial interest.