Options
Human-sized magnetic particle imaging for brain applications
Citation Link: https://doi.org/10.15480/882.2233
Publikationstyp
Journal Article
Date Issued
2019-04-26
Sprache
English
Institut
TORE-DOI
TORE-URI
Journal
Volume
10
Start Page
1
End Page
9
Citation
Nature communications (10): 1-9, art. no. 1936 (2019)
Publisher DOI
Scopus ID
Publisher
Nature Publishing Group
Determining the brain perfusion is an important task for diagnosis of vascular diseases such as occlusions and intracerebral haemorrhage. Even after successful diagnosis, there is a high risk of restenosis or rebleeding such that patients need intense attention in the days after treatment. Within this work, we present a diagnostic tomographic imager that allows access to brain perfusion quantitatively in short intervals. The device is based on the magnetic particle imaging technology and is designed for human scale. It is highly sensitive and allows the detection of an iron concentration of 263 pmolFe ml-1, which is one of the lowest iron concentrations imaged by MPI so far. The imager is self-shielded and can be used in unshielded environments such as intensive care units. In combination with the low technical requirements this opens up a variety of medical applications and would allow monitoring of stroke on intensive care units.
DDC Class
610: Medizin
More Funding Information
German Research Foundation (DFG) grant number KN 1108/2-1
Loading...
Name
s41467-019-09704-x.pdf
Size
3.55 MB
Format
Adobe PDF