Publisher DOI: 10.1093/icvts/ivx289
Title: Novel stent design for transcatheter mitral valve implantation
Language: English
Authors: Loger, Klaas 
Pokorny, Saskia 
Schaller, Tim 
Haben, Irma 
Frank, Derk 
Lutter, Georg 
Issue Date: 9-Oct-2017
Publisher: Oxford Univ. Press
Source: Interactive Cardiovascular and Thoracic Surgery 2 (26): 190-195 (2018-02-01)
Journal or Series Name: Interactive cardiovascular and thoracic surgery 
Abstract (english): OBJECTIVES: In this study, results of a functional in vitro study of 2 newly developed valved stents for transcatheter mitral valve implantation are presented. METHODS: Two novel stent designs, an oval-shaped and a D-shaped stent with a strut fixation system were developed. The fixation force of the novel stents were tested in vitro in porcine hearts with a tensile test set-up. In further experiments, the stents were equipped with a circular valved stent, and the valve performances were investigated in a pulsatile heart valve tester. RESULTS: Sufficient mean stent fixation forces in the range of 24.2 ± 0.9N to 28.6 ± 1.9N were measured for the different stent models. The novel valved stents showed good performance in an in vitro pulsatile heart valve tester. A sufficient opening area and low opening pressures were measured for all tested mitral valved stents. Compared with an established reference valve, the D-shaped stent and the oval-shaped valved stent showed a lower systolic transvalvular pressure gradient, which indicates slightly greater extent of valvular leakage of the closed valved stents. However, the mitral nitinol valved stents demonstrated adequate durability. CONCLUSIONS: This study indicates a sufficient annular fixation force of the tested transcatheter mitral valve implantation valved stent prototypes. Therefore, these mitral valved stents demonstrate a new type of mitral valved stent design.
ISSN: 1569-9285
Institute: Biomechanik M-3 
Type: (wissenschaftlicher) Artikel
Appears in Collections:Publications without fulltext

Show full item record

Page view(s)

Last Week
Last month
checked on Sep 27, 2020

Google ScholarTM


Add Files to Item

Note about this record


Items in TORE are protected by copyright, with all rights reserved, unless otherwise indicated.