Publisher DOI: 10.1016/j.tibtech.2019.03.007
Title: Deep Eutectic Solvents as Efficient Solvents in Biocatalysis
Language: English
Authors: Pätzold, Magdalena 
Siebenhaller, Sascha 
Kara, Selin 
Liese, Andreas  
Syldatk, Christoph 
Holtmann, Dirk 
Issue Date: Sep-2019
Source: Trends in Biotechnology 9 (37): 943-959 (2019-09)
Journal or Series Name: Trends in biotechnology 
Abstract (english): ‘Ideal’ solvents in biocatalysis have to fulfill a large number of requirements, such as high substrate solubility, high enzyme activity and stability, and positive effects on reaction equilibrium. In the past decades, many enzymatic synthesis routes in water-based and nonaqueous (organic solvents, ionic or supercritical fluids) reaction media have been developed. However, no solvent meets every demand for different reaction types at the same time, and there is still a need for novel solvents suited for different reaction types and applications. Deep eutectic solvents (DESs) have recently been evaluated as solvents in different biocatalytic reactions. They can improve substrate supply, conversion, and stability. The best results were obtained when the DES is formed by the substrates of an enzymatic reaction.
URI: http://hdl.handle.net/11420/3136
ISSN: 0167-7799
Institute: Technische Biokatalyse V-6 
Type: (wissenschaftlicher) Artikel
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