Publisher DOI: 10.1109/TRANSDUCERS.2019.8808647
Title: Advances in Manufacturing of Biodegradable Spinal Cord Implants on Microscale through Micromolding and 3D Printing
Language: English
Authors: Poblotzki, Jana von 
Lipka, Timo 
Voss, Christian 
Trieu, Hoc Khiem 
Keywords: 3D Printing;Biodegradable;Implant;Micromolding;Poly(Lactic-co-Glycolic Acid);Spinal Cord Injury
Issue Date: Jun-2019
Source: International Conference on Solid-State Sensors, Actuators and Microsystems and Eurosensors XXXIII : 8808647 (2019-06)
Abstract (english): Spinal cord injury is a life changing event potentially leading to permanent paralysis. This paper presents advances in developing an implant for spinal cord treatment called mechanical microconnector system (mMS). A micromolding process was developed to transfer the mMS from biocompatible to biodegradable material. The results consist of a determined parameter-set for micromolding of biodegradable mMS for two poly(lactic-co-glycolic acid) (PLGA) compounds and polycaprolactone (PCL). The process starts with a complex 3D quartz glass premaster, built through ultrafast laser radiation and subsequent wet-chemical etching (SLE = selective laser induced etching). The incorporation of a 3D printing technique arises from the objective to individualize and automatically produce biodegradable implants out of medical image data in future.
Conference: 20th International Conference on Solid-State Sensors, Actuators and Microsystems and Eurosensors XXXIII, TRANSDUCERS 2019 and EUROSENSORS XXXIII 
URI: http://hdl.handle.net/11420/3371
ISBN: 978-172812007-2
Institute: Mikrosystemtechnik E-7 
Type: InProceedings (Aufsatz / Paper einer Konferenz etc.)
Project: Implantierbarer Mikrokonnektor für die neuroregenerative Behandlung von Querschnittslähmung - QLIMP 
Implantierbarer Mikrokonnektor für die neuroregenerative Behandlung der Querschnittlähmung-QLIMP; Validierung der mMS-Technologie unter Berücksichtigung von Biokompatibilität, Resorbierbarkeit und Individualisierbarkeit am porcinen Model 
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