Publisher DOI: | 10.1109/TRANSDUCERS.2019.8808647 | Title: | Advances in Manufacturing of Biodegradable Spinal Cord Implants on Microscale through Micromolding and 3D Printing | Language: | English | Authors: | Poblotzki, Jana von Lipka, Timo Voss, Christian Trieu, Hoc Khiem |
Keywords: | 3D Printing; Biodegradable; Implant; Micromolding; Poly(Lactic-co-Glycolic Acid); Spinal Cord Injury | Issue Date: | Jun-2019 | Source: | International Conference on Solid-State Sensors, Actuators and Microsystems and Eurosensors XXXIII : 8808647 (2019-06) | Abstract (english): | Spinal cord injury is a life changing event potentially leading to permanent paralysis. This paper presents advances in developing an implant for spinal cord treatment called mechanical microconnector system (mMS). A micromolding process was developed to transfer the mMS from biocompatible to biodegradable material. The results consist of a determined parameter-set for micromolding of biodegradable mMS for two poly(lactic-co-glycolic acid) (PLGA) compounds and polycaprolactone (PCL). The process starts with a complex 3D quartz glass premaster, built through ultrafast laser radiation and subsequent wet-chemical etching (SLE = selective laser induced etching). The incorporation of a 3D printing technique arises from the objective to individualize and automatically produce biodegradable implants out of medical image data in future. |
Conference: | 20th International Conference on Solid-State Sensors, Actuators and Microsystems and Eurosensors XXXIII, TRANSDUCERS 2019 and EUROSENSORS XXXIII | URI: | http://hdl.handle.net/11420/3371 | ISBN: | 978-172812007-2 | Institute: | Mikrosystemtechnik E-7 | Document Type: | Chapter/Article (Proceedings) | Project: | Implantierbarer Mikrokonnektor für die neuroregenerative Behandlung von Querschnittslähmung - QLIMP Implantierbarer Mikrokonnektor für die neuroregenerative Behandlung der Querschnittlähmung-QLIMP; Validierung der mMS-Technologie unter Berücksichtigung von Biokompatibilität, Resorbierbarkeit und Individualisierbarkeit am porcinen Model |
Appears in Collections: | Publications without fulltext |
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