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Publisher DOI: 10.1038/s41598-020-75122-5
Title: Efficient hybrid 3D system calibration for magnetic particle imaging systems using a dedicated device
Language: English
Authors: Gladiß, Anselm von 
Gräser, Matthias  
Behrends, André 
Chen, Xin 
Buzug, Thorsten M. 
Issue Date: 28-Oct-2020
Publisher: Macmillan Publishers Limited
Source: Scientific Reports 1 (10): 18432 (2020)
Journal or Series Name: Scientific reports 
Abstract (english): Image reconstruction in magnetic particle imaging is often performed using a system matrix based approach. The acquisition of a system matrix is a time-consuming calibration which may take several weeks and thus, is not feasible for a clinical device. Due to hardware characteristics of the receive chain, a system matrix may not even be used in similar devices but has to be acquired for each imager. In this work, a dedicated device is used for measuring a hybrid system matrix. It is shown that the measurement time of a 3D system matrix is reduced by 96%. The transfer function of the receive chains is measured, which allows the use of the same system matrix in multiple devices. Equivalent image reconstruction results are reached using the hybrid system matrix. Furthermore, the inhomogeneous sensitivity profile of receive coils is successfully applied to a hybrid system matrix. It is shown that each aspect of signal acquisition in magnetic particle imaging can be taken into account using hybrid system matrices. It is favourable to use a hybrid system matrix for image reconstruction in terms of measurement time, signal-to-noise ratio and discretisation.
DOI: 10.15480/882.3065
ISSN: 2045-2322
Institute: Biomedizinische Bildgebung E-5 
Type: (wissenschaftlicher) Artikel
Funded by: Federal ministry of education and research (BMBF, Grant Nos. 13W0069A and 13GW0230B)
Project: Projekt DEAL 
License: CC BY 4.0 (Attribution) CC BY 4.0 (Attribution)
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