|Publisher DOI:||10.1088/1361-6560/abc09e||Title:||Design of a head coil for high resolution mouse brain perfusion imaging using magnetic particle imaging||Language:||English||Authors:||Gräser, Matthias
Forkert, Nils Daniel
|Keywords:||brain perfusion;coil design;magnetic particle imaging;sensitivity||Issue Date:||25-Nov-2020||Source:||Physics in Medicine and Biology 23 (65): 235007 (2020-11-25)||Journal:||Physics in medicine and biology||Abstract (english):||
Magnetic particle imaging (MPI) is a novel and versatile imaging modality developing toward human application. When up-scaling to human size, the sensitivity of the systems naturally drops as the coil sensitivity depends on the bore diameter. Thus, new methods to push the sensitivity limit further have to be investigated to cope for this loss. In this paper a dedicated surface coil for mice is developed, improving the sensitivity in cerebral imaging applications. Similar to magnetic resonance imaging the developed surface coil improves the sensitivity due to the closer vicinity to the region of interest. With the developed surface coil presented in this work, it is possible to image tracer samples containing only 896 pgfe and detect even small vessels and anatomical structures within a wild type mouse model. As current sensitivity measures require a tracer system a new method for determining a sensitivity measure without this requirement is presented and verified to enable comparison between MPI receiver systems.
|URI:||http://hdl.handle.net/11420/8358||ISSN:||0031-9155||Institute:||Biomedizinische Bildgebung E-5||Document Type:||Article|
|Appears in Collections:||Publications without fulltext|
Show full item record
checked on Dec 2, 2021
checked on Nov 25, 2021
Add Files to Item
Note about this record
Cite this record
Items in TORE are protected by copyright, with all rights reserved, unless otherwise indicated.