|Publisher DOI:||10.1002/cjce.23967||Title:||Process design of a continuous biotransformation with in situ product removal by cloud point extraction||Language:||English||Authors:||Fellechner, Oliver
|Issue Date:||May-2021||Publisher:||Soc.||Source:||The Canadian Journal of Chemical Engineering 99 (5): 1035-1049 (2021-05)||Abstract (english):||
In this work, a continuous, heterogeneous extractive biocatalysis was realized with penicillin G hydrolysis as a model reaction. Therefore, commercially available structured packing CY from Sulzer were coated with enzyme‐containing gels and their catalytic activity was examined. Thereby, the potential of aqueous micellar two‐phase systems (ATPMS) as an extraction medium was evaluated. Triton X‐114 was used as model surfactant. It was found that the separation efficiency of the packing is not affected by the coating and ATPMS allows for a good separation yield. With these results, different process concepts for the continuous, heterogeneous extractive biocatalysis were compared.
|URI:||http://hdl.handle.net/11420/8602||ISSN:||0008-4034||Journal:||The Canadian journal of chemical engineering||Institute:||Thermische Verfahrenstechnik V-8||Document Type:||Article||Project:||Gemischte mizellare Systeme in kontinuierlichen Gegenstromextraktionskolonnen für biokatalysierte reaktive Trennung||Funded by:||Deutsche Forschungsgemeinschaft (DFG)|
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