Dataset for "Oxygen-dependent redox control enables growth-decoupled biotransformations in Cupriavidus necator"
Citation Link: https://doi.org/10.15480/882.16935
Type
Dataset
Version
v1.0
Date Issued
2026-04-07
Data Curator
Language
English
TORE-DOI
Used equipment
Is Supplement To
Abstract
This dataset contains measurements from growth and cell suspension experiments using engineered Cupriavidus necator strains for oxygen-dependent biotransformations. Experiments include: Acetoin reduction to 2,3-butanediol under ±O₂; Glycerol conversion to 1,3-propanediol under ±O₂; Growth experiments under oxic conditions; Long-term viability assays with live/dead staining. Oxygen availability was used as a control parameter to modulate intracellular redox metabolism and direct NADH utilization toward either product formation or respiration.
Subjects
Cupriavidus necator
redox metabolism
oxygen limitation
acetoin
2,3-butanediol
1,3-propanediol
HPLC
DDC Class
660.6: Biotechnology
More Funding Information
This project is funded by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) – SFB 1615 – 503850735.