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Item type:Publication, Access status: without files , Intelligente Implantate für das Monitoring der Knochenheilung(Springer, 2013-11-30); ; ; ; Background: Monitoring of fracture healing is a complex problem. Radiographs solely enable the estimation of calcification. Telemetric determination of bone healing: A telemetric system to mechanically assess bone healing was developed. The system consists of an electronic unit applied to a locked plate, an external reader and a ground sensor to measure externally applied loads. By correlating the externally applied load and deformation in the implant, the elasticity of the osteosynthesis is calculated. Elasticity decreases with ongoing consolidation of a fracture or nonunion and is appropriate to monitor the course of bone healing. Clinical application: Clinical application was performed in 56 patients suffering nonunions or a fracture of the femur; in 47 cases treatment was completed. In 46 of 47 patients, consolidation was achieved. Different types of healing curves could be differentiated (fast healing, slow healing, plateau with following fast healing, nonhealing). Conclusion: The system proved to be valuable for the judgement of bone healing in difficult healing situations. Routine cost-effective manufacturing is possible, because the used electronic components are derived from mass products.Publicationtype: Journal Article95 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Access status: without files , Telemetric assessment of bone healing with an instrumented internal fixator : a preliminary study(American Orthopaedic Association, 2011-11-01); ; ; ; In an interdisciplinary project involving electronic engineers and clinicians, a telemetric system was developed to measure the bending load in a titanium internal femoral fixator. As this was a new device, the main question posed was: what clinically relevant information could be drawn from its application? As a first clinical investigation, 27 patients (24 men, three women) with a mean age of 38.4 years (19 to 66) with femoral nonunions were treated using the system. The mean duration of the nonunion was 15.4 months (5 to 69). The elasticity of the plate-callus system was measured telemetrically until union. Conventional radiographs and a CT scan at 12 weeks were performed routinely, and healing was staged according to the CT scans. All nonunions healed at a mean of 21.5 weeks (13 to 37). Well before any radiological signs of healing could be detected, a substantial decrease in elasticity was recorded. The relative elasticity decreased to 50% at a mean of 7.8 weeks (3.5 to 13) and to 10% at a mean of 19.3 weeks (4.5 to 37). At 12 weeks the mean relative elasticity was 28.1% (0% to 56%). The relative elasticity was significantly different between the different healing stages as determined by the CT scans. Incorporating load measuring electronics into implants is a promising option for the assessment of bone healing. Future application might lead to a reduction in the need for exposure to ionising radiation to monitor fracture healing. ©2012 British Editorial Society of Bone and Joint Surgery.Publicationtype: Journal Article107