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Item type:Publication, Access status: without files , Hemodynamics in arterial bypass graft anastomoses with varying cuff sizes and proximal flow paths: a fluid–structure interaction studyThis article investigates the effect of the cuff size of arterial bypass grafts and the flow conditions on the hemodynamics in the anastomosis (connection) to the artery, using numerical simulations. We consider a fluid-structure interaction problem which is solved based on a partitioned scheme. Additionally, we employ computational fluid dynamics to investigate the effect of a rigid wall assumption. The work focuses on clinically relevant hemodynamic quantities associated with the development of intimal hyperplasia. We also include a model for the prediction of hemolysis into the simulation. The results show that even minor changes of the cuff size can result into significant differences in the corresponding quantities of interest. The importance of the inflow path is shown to be lower than that of the cuff size. The usually employed rigid wall assumption is found to be adequate to address wall shear stress oscillations but falls short on predicting maximum and minimum wall shear stress-related quantities of interest.Publicationtype: Journal Article29 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Access status: without files , A fluid-structure interaction study of hemodynamics in arterial bypass-graft anastomoses(2022-06); ; ; This paper reports on numerical experiments on arterial bypass-graft anastomoses. Bypass-grafts are oftentimes used in surgical procedures to divert blood around narrowed or occluded parts of an artery. The diverted blood flow is crucial to the success of the operation as it may lead to undesirable peculiarities that can result to a renewed occlusion in the distal connection of the graft. However, an a priori prediction of detrimental hemodynamic aspects due to undesirable flow properties is difficult to perform in vitro or in vivo conditions. To this end, this work targets to enhance our understanding of harming mechanisms through in silico experiments using computational fluid dynamics (CFD) and fluid-structure interaction (FSI) simulations. The latter are realized through a partitioned coupled approach which is verified for a 2D benchmark case against literature-reported results. Finally, we present numerical results on grafts with different cuff sizes. Wall shear stress (WSS), oscillatory shear index (OSI) and hemolysis are monitored and compared in the context of either rigid or elastic walls and cuff sizes. Special interest is given to the prediction of hemolysis induction which is often not considered in such studies. We show that wall elasticity is the key parameter in terms of WSS prediction while cuff size mainly affects the estimation of OSI.Publicationtype: Conference Paper47