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Item type:Publication, Access status: without files , Standardized qualification of stirred bioreactors for microbial biopharmaceutical production processes(Wiley-VCH, 2017-10-20); ; ; ; An in 2016 published DECHEMA guideline concerning process engineering characterization and a new Escherichia coli model process were utilized for the qualification of two geometrically similar stirred stainless steel bioreactors (30 L and 100 L working volume). The achieved results demonstrate that performing an additional biological model process is a valuable complement to the process engineering characterization. Optical densities of 27 (100 L) and 39 (30 L) were reached in the batch cultivation process.Publicationtype: Journal Article85