DC FieldValueLanguage
dc.contributor.authorGräser, Matthias-
dc.contributor.authorLudewig, Peter-
dc.contributor.authorSzwargulski, Patryk-
dc.contributor.authorFörger, Fynn-
dc.contributor.authorLiebing, Tom-
dc.contributor.authorForkert, Nils Daniel-
dc.contributor.authorThieben, Florian-
dc.contributor.authorMagnus, Tim-
dc.contributor.authorKnopp, Tobias-
dc.date.accessioned2021-01-08T13:16:23Z-
dc.date.available2021-01-08T13:16:23Z-
dc.date.issued2020-11-25-
dc.identifier.citationPhysics in Medicine and Biology 23 (65): 235007 (2020-11-25)de_DE
dc.identifier.issn0031-9155de_DE
dc.identifier.urihttp://hdl.handle.net/11420/8358-
dc.description.abstractMagnetic particle imaging (MPI) is a novel and versatile imaging modality developing toward human application. When up-scaling to human size, the sensitivity of the systems naturally drops as the coil sensitivity depends on the bore diameter. Thus, new methods to push the sensitivity limit further have to be investigated to cope for this loss. In this paper a dedicated surface coil for mice is developed, improving the sensitivity in cerebral imaging applications. Similar to magnetic resonance imaging the developed surface coil improves the sensitivity due to the closer vicinity to the region of interest. With the developed surface coil presented in this work, it is possible to image tracer samples containing only 896 pgfe and detect even small vessels and anatomical structures within a wild type mouse model. As current sensitivity measures require a tracer system a new method for determining a sensitivity measure without this requirement is presented and verified to enable comparison between MPI receiver systems.en
dc.language.isoende_DE
dc.relation.ispartofPhysics in medicine and biologyde_DE
dc.subjectbrain perfusionde_DE
dc.subjectcoil designde_DE
dc.subjectmagnetic particle imagingde_DE
dc.subjectsensitivityde_DE
dc.titleDesign of a head coil for high resolution mouse brain perfusion imaging using magnetic particle imagingde_DE
dc.typeArticlede_DE
dc.type.diniarticle-
dcterms.DCMITypeText-
tuhh.abstract.englishMagnetic particle imaging (MPI) is a novel and versatile imaging modality developing toward human application. When up-scaling to human size, the sensitivity of the systems naturally drops as the coil sensitivity depends on the bore diameter. Thus, new methods to push the sensitivity limit further have to be investigated to cope for this loss. In this paper a dedicated surface coil for mice is developed, improving the sensitivity in cerebral imaging applications. Similar to magnetic resonance imaging the developed surface coil improves the sensitivity due to the closer vicinity to the region of interest. With the developed surface coil presented in this work, it is possible to image tracer samples containing only 896 pgfe and detect even small vessels and anatomical structures within a wild type mouse model. As current sensitivity measures require a tracer system a new method for determining a sensitivity measure without this requirement is presented and verified to enable comparison between MPI receiver systems.de_DE
tuhh.publisher.doi10.1088/1361-6560/abc09e-
tuhh.publication.instituteBiomedizinische Bildgebung E-5de_DE
tuhh.type.opus(wissenschaftlicher) Artikel-
dc.type.driverarticle-
dc.type.casraiJournal Article-
tuhh.container.issue23de_DE
tuhh.container.volume65de_DE
dc.identifier.scopus2-s2.0-85098571030de_DE
tuhh.container.articlenumber235007de_DE
item.creatorOrcidGräser, Matthias-
item.creatorOrcidLudewig, Peter-
item.creatorOrcidSzwargulski, Patryk-
item.creatorOrcidFörger, Fynn-
item.creatorOrcidLiebing, Tom-
item.creatorOrcidForkert, Nils Daniel-
item.creatorOrcidThieben, Florian-
item.creatorOrcidMagnus, Tim-
item.creatorOrcidKnopp, Tobias-
item.languageiso639-1en-
item.creatorGNDGräser, Matthias-
item.creatorGNDLudewig, Peter-
item.creatorGNDSzwargulski, Patryk-
item.creatorGNDFörger, Fynn-
item.creatorGNDLiebing, Tom-
item.creatorGNDForkert, Nils Daniel-
item.creatorGNDThieben, Florian-
item.creatorGNDMagnus, Tim-
item.creatorGNDKnopp, Tobias-
item.openairetypeArticle-
item.grantfulltextnone-
item.openairecristypehttp://purl.org/coar/resource_type/c_6501-
item.mappedtypeArticle-
item.fulltextNo Fulltext-
item.cerifentitytypePublications-
crisitem.author.deptBiomedizinische Bildgebung E-5-
crisitem.author.deptBiomedizinische Bildgebung E-5-
crisitem.author.deptBiomedizinische Bildgebung E-5-
crisitem.author.deptBiomedizinische Bildgebung E-5-
crisitem.author.deptBiomedizinische Bildgebung E-5-
crisitem.author.orcid0000-0003-1472-5988-
crisitem.author.orcid0000-0001-9025-6402-
crisitem.author.orcid0000-0003-2563-9006-
crisitem.author.orcid0000-0002-3865-4603-
crisitem.author.orcid0000-0003-3162-4783-
crisitem.author.orcid0000-0003-2556-3224-
crisitem.author.orcid0000-0002-2890-5288-
crisitem.author.orcid0000-0002-1589-8517-
crisitem.author.parentorgStudiendekanat Elektrotechnik, Informatik und Mathematik-
crisitem.author.parentorgStudiendekanat Elektrotechnik, Informatik und Mathematik-
crisitem.author.parentorgStudiendekanat Elektrotechnik, Informatik und Mathematik-
crisitem.author.parentorgStudiendekanat Elektrotechnik, Informatik und Mathematik-
crisitem.author.parentorgStudiendekanat Elektrotechnik, Informatik und Mathematik-
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