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Item type:Publication, Access status: without files , The role of patient-mode high-resolution peripheral quantitative computed tomography indices in the prediction of failure strength of the elderly women’s thoracic vertebral bodyResults: For the prediction of vertebral failure load, the inclusion of BV/TV into L1 aBMD was the best model (R2 = 0.52), Tb.N and Tb.Sp added significant information to the L1 aBMD and to the cortical BMD, but none of the vertebral microarchitectural parameters yielded additional significant information to the trabecular BMD (or BV/TV) and to the vertebral BMD.Publicationtype: Journal ArticleScopus© Citations 14 30 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Access status: without files , Mechanical behavior of screws in normal and osteoporotic boneFracture fixation in severe osteoporotic bone by means of implants that rely on screw anchorage is still a clinical problem. So far, a sufficiently accurate prediction of the holding capacity of screws as a function of local bone morphology has not been obtained. In this study the ultimate pullout loads of screws in the epi-, meta-, and diaphyseal regions of human tibiae were correlated to the cortical thicknesses and cancellous bone mineral densities at the screw axes determined from QCT densitometric data. Stepwise multiple linear regression showed that in regions with cortical thicknesses below 1.5 mm, cancellous density determined the ultimate pullout load (R2=0.85, p<0.001), while in regions with cortices above 1.5 mm, cortical thickness alone significantly influenced the holding capacity of a screw (R2=0.90, p<0.001). The findings of this study provide a basis for a bone morphology-related pre-operative estimation of the holding capacity of screws, which could help to improve their proper application in osteoporotic bone.Publicationtype: Journal Article10