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Item type:Publication, Access status: without files , Design for X-ray: design strategies for radiographically unobtrusive FFF functional components(2026-10); ; ; Fused Filament Fabrication (FFF) components are frequently used in physical medical training models to position, support, or integrate anatomical structures. In X-ray-based training environments, these parts must fulfill their mechanical functions while minimizing unwanted visibility in fluoroscopy. This contribution investigates how infill structure, external geometry, and projection direction influence the radiographic appearance of FFF components. Experimental X-ray imaging of test specimens is combined with G-Code-based virtual X-ray simulation to derive initial design principles. The approach is applied to a representative vascular support in the neurointerventional simulator HANNES, demonstrating how radiological unobtrusiveness can be addressed as an explicit design objective.Publicationtype: Conference Paper6 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Access status: with files , Development and validation of a novel stenosis model for percutaneous transluminal angioplasty training of the internal carotid arteryIntroduction/Background: The rising demand for endovascular stroke therapy highlights the need for standardized training environments. Studies have shown the positive impact of simulator-based training for neurointerventional procedures. Given the frequent use of percutaneous transluminal angioplasty (PTA) of the internal carotid artery (ICA) in acute settings, specialized simulation training is crucial. This study evaluates the feasibility of a custom-made ICA stenosis model for PTA simulation. Methods: Internally developed 3D-printed circular clamps were attached to patient-based 3D printed ICA models and integrated into a previously described realistic whole-body neurovascular simulation model HANNES (Hamburg Anatomic Neurointerventional Endovascular Simulator) to simulate a proximal ICA stenosis. Participants (N = 5) of varying experience levels each performed three PTA procedures. Fluoroscopy time, radiation doses, and the extent of stenosis and balloon inflation pressure were assessed. After simulation, participants rated the model in terms of haptic, feasibility and applicability. Results: For statistical analysis, the participants were divided into two groups according to their experience level. There was a statistically significant difference in the procedure duration between both groups, U = 10.500, Z = −1.968, p < 0.05. Significant test results could also be demonstrated for radiation doses (DAP) among groups, Kolmogorov-Smirnov p < 0.05, U = 7.000, Z = −2.357, p < 0.05. No difference was shown between the total contrast volume (ml) among groups that was used during procedures (m = 11.67, SD 2.09). Conclusion: The authors propose a novel ICA stenosis simulation model for training of the cervical PTA. The model provides a realistic and replicable method for standardized procedural training.Publicationtype: Journal Article31 12 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Access status: with files , Design and experimental validation of a novel additively manufactured stenosis model for neurointerventional training(Infinite Science Publishing, 2025-06-02); ; ; ; Stenoses, or pathological narrowings of blood vessels, are significant risk factors for cardiovascular events. While various stenosis models exist for training purposes, they often present limitations for intracranial applications due to their size and inability to maintain vessel dilation after treatment. This paper presents the development and evaluation of a novel stenosis model specifically designed for compact, intracranial applications within the neurointerventional simulator HANNES. The model utilizes a C-shaped clip mechanism that selectively constricts an elastic vessel, incorporating a designed breaking point that ensures permanent vessel dilation upon reaching a critical pressure during balloon angioplasty. The model was manufactured using stereolithographic additive manufacturing and underwent experimental evaluation using a standard PTA balloon catheter. Results demonstrated reproducible burst pressures of 12 ± 1 bar, aligning with typical clinical parameters. X-ray imaging confirmed successful integration into the HANNES simulator, enabling realistic simulation of stenosis treatment procedures. Experiments showed that the developed stenosis model should be used with elastic silicone tubes connected to additively manufactured vessel models, as direct application to printed vessels either resulted in vessel wall damage during compression or insufficient constriction depending on the C-clip geometry. Based on these findings and the successful validation results, the model represents a reliable and reproducible platform for neurointerventional training, with its parametric design allowing adaptation to various clinical scenarios.Publicationtype: Journal Article11 11 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Access status: without files , Quantitative analysis of periprocedural thrombus fragmentation using an automated optical detection system in a comprehensive stroke intervention training platform(American Society of Mechanical Engineers (ASME), 2025-04); ; ; ; Mechanical thrombectomy for occluded large brain vessels in acute ischemic stroke has proven highly effective, but periprocedural thrombus fragmentation (PTF) remains a significant challenge that can lead to downstream embolization and incomplete recanalization. While laboratory methods exist for detailed PTF analysis, practical solutions are needed for quantitative assessment of simulated thrombectomy procedures performed on physical training models. We present a novel measurement system that enables automated detection and quantification of thrombus fragmentation events during simulated thrombectomy procedures on the HANNES neurointerventional simulator. The system employs a six-channel measurement chamber with integrated UV illumination and an optical detection setup to track fluorescent thrombus fragments. Fragments are automatically detected, assigned IDs, and measured in real-time using computer vision techniques. Validation studies comparing the system's measurements to microscopic analysis demonstrated strong correlation (Pearson's r=0.9939, p<0.001). In controlled testing, the system achieved 100% sensitivity and specificity for single fragment detection, successfully measuring fragments as small as 642 μm in radius. While adhering fragments are currently treated as single entities, the system's ability to automatically track and quantify PTF events in real-time provides an objective basis for evaluating procedural performance and comparing thrombectomy techniques in training scenarios. This novel measurement system represents a practical advance for studying thrombus fragmentation in educational settings. Integration into comprehensive training platforms like HANNES could improve understanding and management of PTF risks, potentially leading to better patient outcomes through enhanced operator training. Future studies correlating PTF metrics with physician experience and clinical results may establish performance benchmarks to help quantify individual proficiency and predict clinical competency.Publicationtype: Conference Paper40 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Access status: without files , P165/237 Development and Validation of a novel stenosis model for percutaneous transluminal angioplasty training(BMJ Publishing Group, 2023-08-21); ; ; ; The continuously expanding field of neurointervention with its increasing demand in endovascular therapy of ischemic stroke urges for the establishment of standardized procedural training environments. Studies have already shown the positive impact of simulator-based training for neurointerventional procedures. Stent-protected percutaneous angioplasty of the ICA is often performed in the acute setting and thus, simulation training is indispensable.Aim of Study: In this context we aim to analyze the feasibility of a custom-made stenosis model of the internal carotid artery by means of percutaneous transluminal angioplasty. Methods Internally developed 3D-printed circular clamps were attached to patient-based 3D printed ICA models and integrated in a previously described realistic whole-body neurovascular simulation model. Participants (N=5) with different levels of experience performed PTA (N=15). Fluoroscopy time, radiation doses,extent of stenosis and balloon inflation pressure were assessed. After simulation, participants rated qualitatively the model in terms of haptic, feasibility and applicability of the model. Results Participants declared an overall agreement concerning the beneficial use of the simulation model. A median stenosis degree of 83% could be achieved. Lumen could be normalised using ballon angioplasty in all cases. Balloon inflation pressure was in most cases comparable to in-vivo procedure (median 13 kPA). No significant difference was seen in fluoroscopy time and radiation dose among participants. Conclusion The authors propose a novel ICA stenosis simulation model for training of PTA.The model provides a realistic and replicable method for standardized procedural training. Disclosure of Interest Nothing to disclose.Publicationtype: Journal Article31