Settings

Now showing1 - 2 of 2
  • Some of the metrics are blocked by your 
    consent settings
    Item type:Publication, Access status: with files ,
    Development and validation of a novel stenosis model for percutaneous transluminal angioplasty training of the internal carotid artery
    (Springer, 2026)
    Ramdani, Nora
    ;
    Kyselyova, Anna
    ;
    MacMillan, Nadine
    ;
    Ngo, Ngoc Tuan
    ;
    Schmiech, Jonte
    Introduction/Background: The rising demand for endovascular stroke therapy highlights the need for standardized training environments. Studies have shown the positive impact of simulator-based training for neurointerventional procedures. Given the frequent use of percutaneous transluminal angioplasty (PTA) of the internal carotid artery (ICA) in acute settings, specialized simulation training is crucial. This study evaluates the feasibility of a custom-made ICA stenosis model for PTA simulation. Methods: Internally developed 3D-printed circular clamps were attached to patient-based 3D printed ICA models and integrated into a previously described realistic whole-body neurovascular simulation model HANNES (Hamburg Anatomic Neurointerventional Endovascular Simulator) to simulate a proximal ICA stenosis. Participants (N = 5) of varying experience levels each performed three PTA procedures. Fluoroscopy time, radiation doses, and the extent of stenosis and balloon inflation pressure were assessed. After simulation, participants rated the model in terms of haptic, feasibility and applicability. Results: For statistical analysis, the participants were divided into two groups according to their experience level. There was a statistically significant difference in the procedure duration between both groups, U = 10.500, Z = −1.968, p < 0.05. Significant test results could also be demonstrated for radiation doses (DAP) among groups, Kolmogorov-Smirnov p < 0.05, U = 7.000, Z = −2.357, p < 0.05. No difference was shown between the total contrast volume (ml) among groups that was used during procedures (m = 11.67, SD 2.09). Conclusion: The authors propose a novel ICA stenosis simulation model for training of the cervical PTA. The model provides a realistic and replicable method for standardized procedural training.
    Publicationtype: Journal Article
      31  12
  • Some of the metrics are blocked by your 
    consent settings
    Item type:Publication, Access status: with files ,
    Design and experimental validation of a novel additively manufactured stenosis model for neurointerventional training
    (Infinite Science Publishing, 2025-06-02)
    Schmiech, Jonte
    ;
    De Sousa Guerreiro, Helena I.
    ;
    Sobirey, Eve
    ;
    Wieland, Philipp
    ;
    Ramdani, Nora
    Stenoses, or pathological narrowings of blood vessels, are significant risk factors for cardiovascular events. While various stenosis models exist for training purposes, they often present limitations for intracranial applications due to their size and inability to maintain vessel dilation after treatment. This paper presents the development and evaluation of a novel stenosis model specifically designed for compact, intracranial applications within the neurointerventional simulator HANNES. The model utilizes a C-shaped clip mechanism that selectively constricts an elastic vessel, incorporating a designed breaking point that ensures permanent vessel dilation upon reaching a critical pressure during balloon angioplasty. The model was manufactured using stereolithographic additive manufacturing and underwent experimental evaluation using a standard PTA balloon catheter. Results demonstrated reproducible burst pressures of 12 ± 1 bar, aligning with typical clinical parameters. X-ray imaging confirmed successful integration into the HANNES simulator, enabling realistic simulation of stenosis treatment procedures. Experiments showed that the developed stenosis model should be used with elastic silicone tubes connected to additively manufactured vessel models, as direct application to printed vessels either resulted in vessel wall damage during compression or insufficient constriction depending on the C-clip geometry. Based on these findings and the successful validation results, the model represents a reliable and reproducible platform for neurointerventional training, with its parametric design allowing adaptation to various clinical scenarios.
    Publicationtype: Journal Article
      11  11